Chapter 20 - Microtubules

Daughter cells

________ are created during cytokinesis through cleavage.

Microproteins Bimc

________, CENP- E, and cytosolic dynein move into and stay in all spindles.

GTPases

________ have a branch of tubulin that belong to the same family, and those tubulins polymerize into microtubules which are small hollow cylindrical structures which a diameter of 25 nm.

dyneins

Dynactin links ________ to their cargoes which consist of vesicles and chromosomes.

Dynactin

________ is a multiprotein complex that also works to bind microtubules.

Kinesins

________ work as dimers with head domains that bind microtubules and ATP and tail domains that bind other cargo or vesicles.

Protofilaments

________ are formed by dimeric aB- tubulin which interact with end to end, and ________ are laterally associated with microtubules.

structural polarity

The (+) of microtubules lose and gain subunits, and microtubules have ________.

Drugs

________ like colchicine and taxol can help with cancer as they disrupt microtubules and provide an antimitotic effect.

MAPs

________ can control cytosolic microtubule depolymerization.

microtubule dynamics

Both ________ and microtubule motors are needed for chromosomal transport to the opposite poles at anaphase.

Mitosis

________ is the process of replicated chromosomes being separated and partitioned into two daughter cells.

Motor protein

________- mediated interactions help establish the orientation of spindles.

Kinesins

________ move cargo to the (+) side and dyneins move cargo to the-) (side.