________ and kinase cascades help make signaling pathways more powerful.
2
New cards
GPCR arrestin complex
________ initiates cytosolic kinases, and those cascades lead to the activation of cell growth controlling genes.
3
New cards
CGMP synthesis
________ leads to protein kinase G being activated in vascular smooth muscle cells, which help with the muscles relaxation.
4
New cards
PKA
________ has two effects on liver and muscle cells:
5
New cards
Hormone
________ occupied receptors initiate the binding of GTP in the cell, causing Ga to interact with an effector protein.
6
New cards
Light
________- activated ospin and the binding of arrestin to phosphorylated ospin activate transducin,
7
New cards
Trimeric G
________ proteins convert into effector proteins, which help with either becoming another form of messengers or channel proteins in the cells.
8
New cards
lipid rafts
When receptors and proteins cluster together, they form ________, which promote the interaction between signaling proteins and this enhances signal transduction.
9
New cards
IP3
________ opens ________- gated Ca2+ channels in the endoplasmic reticulum.
10
New cards
Ca2+ calmodulin complex
________ helps with the regulation of many different proteins:
11
New cards
Kinase A
________ (PKA) can lead to phosphorylation of CREB protein, and with the CBP /300 coactivator, can cause the transcription of target genes.
12
New cards
Nonprotein intracellular signaling molecules
________ help with the regulation of enzymatic and nonenzymatic proteins.