Chapter 6 - Integrating Cells into Tissues

LG domains

LG domains

________ are found in a wide variety of proteins and can mediate binding to steroids and proteins as well as carbohydrates.

Tight junctions

________ prevent the diffusion of macromolecules and to varying degrees impede the diffusion of small water- soluble molecules and ions across an epithelial sheet in the spaces between cells.

self association

The force needed to unfold and expose functional ________ sites in fibronectin is much less than that needed to disrupt fibronectin- integrin- binding.

Stems

________ have support and transport functions; roots provide anchorage and absorb and store nutrients; leaves are the sites of photosynthesis, and flowers enclose the reproductive structures.

Hemidesmosomes

________ found mainly on the basal surface of epithelial cells, anchor an epithelium to components of the underlying extracellular matrix.

family of multi adhesive proteins

Laminins**, a(n) ________ that form a fibrous two- dimensional network with type IV collagen and that also bind to integrins.

morphogenesis

First expressed during ________, NCAMs play an important role in the differentiation of muscle, glial, and nerve cells.

extracellular matrix

Is one of more than 20 types of collagen that participate in the formation of the ________ in various tissues.

tight adhesion

For ________ to occur between activated endothelial cells and leukocytes, B2- containing integrins on the surfaces of leukocytes also must be activated by chemokines or other local activation signals such as platelet- activating factor.