Transplant Rejection Mechanisms

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Biology

Immunology

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7 Terms

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Transplant rejection
________ can occur if recipient immune system recognizes donor alloantigens.
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Alloantibodies
________ develop after exposure to alloantigens in previous grafts, blood transfusion, or after pregnancy.
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Overtime alloantibodies
________ cause inflammation in graft + form immune complexes that are deposited in graft vasculature.
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Chronic Rejection
________: occurs many months /years after graft has been placed.
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Allograft
________: tissue transplantation between genetically distinct individuals of the same species.
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Hyperacute rejection
________: occurs when recipient has pre- existing Ab to alloantigens.
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Alloreactive T cells
________ recognize MHC allotypes on donor dendritic as foreign.