Chapter 18 - Metabolism and Movement of Lipids

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Biology

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cytosolic leaflets

The exoplasmic and ________ distribute membrane phospholipids.

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Infection

________ or injury can cause inflammatory responses in the artery wall, which cause foam cells that show atherosclerosis.

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ER

The synthesizing final steps are catalyzed by membrane associations in the ________, Golgi, mitochondria, and peroxisomes.

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StAR proteins

________ move cholesterol through the mitochondria for the function of steroid hormone synthesis.

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atherosclerotic plaques

If the ________ cause partial or complete blockage of the coronary arteries then the heart can not get its needed nutrients, which can ultimately cause a heart attack (similarly, this happening to the brain causes a stroke)

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cytosol

The ________ is the main base for the initial steps in cholesterol biosynthesis, and the last steps take place in the ER membrane.

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Fatty acids

________ are composed of:

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8

NPC1

________ is needed for cholesterol to move normally into intracellular compartments.

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ABC

The ________ superfamily, which is made of ATP hydrolyzing small molecule pumps, controls ________ proteins which control the export of lipids in the cells.

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HMG CoA reductase

________ catalyzes the rate- controlling step required for cholesterol biosynthesis.

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Plasma LDL

________ (bad cholesterol) causes the formation of foam cells.

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