The integumentary system is the body's largest organ system.
Comprises skin, hair, nails, and associated glands.
Functions as a protective barrier, regulates temperature, and provides sensory information.
Epidermis:
Outermost layer, composed of stratified squamous epithelium.
Contains keratinocytes (produce keratin), melanocytes (produce melanin), and Langerhans cells (immune response).
Dermis:
Beneath the epidermis, thicker layer.
Contains connective tissue, blood vessels, nerves, hair follicles, and glands.
Divided into two layers:
Papillary Layer: Contains dermal papillae, increases surface area for exchange.
Reticular Layer: Dense irregular connective tissue, provides strength and elasticity.
Hypodermis (Subcutaneous Layer):
Not part of the skin but supports it.
Composed of loose connective tissue and fat, insulates and absorbs shock.
Composed of keratinized cells.
Functions: protection, regulation of body temperature, and sensory perception.
Hair follicles are embedded in the dermis.
Protect the distal phalanx and enhance fine touch.
Composed of hard keratin.
Nail growth occurs at the nail matrix.
Sebaceous Glands:
Produce sebum (oil) to lubricate skin and hair.
Sweat Glands:
Eccrine Glands: Regulate body temperature through sweat.
Apocrine Glands: Associated with hair follicles, produce thicker sweat, activated during stress or sexual arousal.
Protection: Shields against pathogens, UV radiation, and physical injury.
Temperature Regulation: Through sweat production and blood flow adjustments.
Sensation: Contains receptors for touch, pressure, pain, and temperature.
Metabolic Functions: Synthesizes vitamin D upon UV exposure, important for calcium metabolism.
Excretion: Eliminates waste products through sweat.
Acne: Inflammation of sebaceous glands.